Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Methylthioadenosine Phosphorylase (MTAP) in Tissue homogenates and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Methylthioadenosine Phosphorylase (MTAP) in Tissue homogenates and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Methylthioadenosine Phosphorylase (MTAP) in Tissue homogenates and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Methylthioadenosine Phosphorylase (MTAP) in Tissue homogenates and other biological fluids.

Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Methylthioadenosine Phosphorylase (MTAP) in samples from Tissue homogenates and other biological fluids. with no significant corss-reactivity with analogues from other species.

Description: Recombinant Human Methylthioadenosine Phosphorylase expressed in: E.coli

Description: Recombinant Mouse Methylthioadenosine Phosphorylase expressed in: E.coli

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Methylthioadenosine Phosphorylase (MTAP) in Tissue homogenates and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Methylthioadenosine Phosphorylase (MTAP) in Tissue homogenates and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Methylthioadenosine Phosphorylase (MTAP) in Tissue homogenates and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Methylthioadenosine Phosphorylase (MTAP) in Tissue homogenates and other biological fluids.

Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mouse Methylthioadenosine Phosphorylase (MTAP) in samples from Tissue homogenates and other biological fluids. with no significant corss-reactivity with analogues from other species.

Description: A sandwich ELISA kit for detection of Methylthioadenosine Phosphorylase from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Description: A sandwich ELISA kit for detection of Methylthioadenosine Phosphorylase from Mouse in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Description: A Rabbit polyclonal antibody against Human Methylthioadenosine Phosphorylase (MTAP)

Description: A Rabbit polyclonal antibody against Human Methylthioadenosine Phosphorylase (MTAP). This antibody is labeled with APC.

Description: A Rabbit polyclonal antibody against Human Methylthioadenosine Phosphorylase (MTAP). This antibody is labeled with Biotin.

Description: A Rabbit polyclonal antibody against Human Methylthioadenosine Phosphorylase (MTAP). This antibody is labeled with Cy3.

Description: A Rabbit polyclonal antibody against Human Methylthioadenosine Phosphorylase (MTAP). This antibody is labeled with FITC.

Description: A Rabbit polyclonal antibody against Human Methylthioadenosine Phosphorylase (MTAP). This antibody is labeled with HRP.

Description: A Rabbit polyclonal antibody against Human Methylthioadenosine Phosphorylase (MTAP). This antibody is labeled with PE.

Description: A Rabbit polyclonal antibody against Human, Mouse Methylthioadenosine Phosphorylase (MTAP)

Description: A Rabbit polyclonal antibody against Human Methylthioadenosine Phosphorylase (MTAP). This antibody is labeled with APC-Cy7.

Description: A Rabbit polyclonal antibody against Human, Mouse Methylthioadenosine Phosphorylase (MTAP). This antibody is labeled with APC.

Description: A Rabbit polyclonal antibody against Human, Mouse Methylthioadenosine Phosphorylase (MTAP). This antibody is labeled with Biotin.

Description: A Rabbit polyclonal antibody against Human, Mouse Methylthioadenosine Phosphorylase (MTAP). This antibody is labeled with Cy3.

Description: A Rabbit polyclonal antibody against Human, Mouse Methylthioadenosine Phosphorylase (MTAP). This antibody is labeled with FITC.

Description: A Rabbit polyclonal antibody against Human, Mouse Methylthioadenosine Phosphorylase (MTAP). This antibody is labeled with HRP.

Description: A Rabbit polyclonal antibody against Human, Mouse Methylthioadenosine Phosphorylase (MTAP). This antibody is labeled with PE.

Description: A Rabbit polyclonal antibody against Human, Mouse Methylthioadenosine Phosphorylase (MTAP). This antibody is labeled with APC-Cy7.

Description: Ki = 62 ?M for S49-derived high-affinity cAMP phosphodiesterase Methylthioadenosine (MTA) is a naturally occurring sulfur-containing nucleoside in all mammalian tissues.

Description: Ki = 62 ?M for S49-derived high-affinity cAMP phosphodiesterase Methylthioadenosine (MTA) is a naturally occurring sulfur-containing nucleoside in all mammalian tissues.

Description: Description of target: This gene encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage of both adenine and methionine. The encoded enzyme is deficient in many cancers because this gene and the tumor suppressor p16 gene are co-deleted. Multiple alternatively spliced transcript variants have been described for this gene, but their full-length natures remain unknown.;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.063 ng/mL

Description: Description of target: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.UniRule annotation <p>Manual validated information which has been generated by the UniProtKB automatic annotation system.</p> <p><a href="/manual/evidences#ECO:0000255">More…</a></p> Manual assertion according to rulesiHAMAP-Rule:MF_031551 Publication <p>Manually curated information for which there is published experimental evidence.</p> <p><a href="/manual/evidences#ECO:0000269">More…</a></p> Manual assertion based on experiment iniRef.8"Purification and characterization of 5'-deoxy-5'-methylthioadenosine phosphorylase from human placenta."_x005F_x005F_x000D_Della Ragione F., Carteni-Farina M., Gragnaniello V., Schettino M.I., Zappia V._x005F_x005F_x000D_J. Biol. Chem. 261:12324-12329(1986) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION, BIOPHYSICOCHEMICAL PROPERTIES, SUBUNIT. ;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: < 0.063 ng/mL

Description: Description of target: This gene encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage of both adenine and methionine. The encoded enzyme is deficient in many cancers because this gene and the tumor suppressor p16 gene are co-deleted. Multiple alternatively spliced transcript variants have been described for this gene, but their full-length natures remain unknown.;Species reactivity: Human;Application: ;Assay info: Quantitative Sandwich ELISA;Sensitivity: < 0.063 ng/mL

Description: Description of target: ;Species reactivity: Mouse;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 39pg/mL

Description: Description of target: Catalyzes the reversible phosphorylation of s-methyl-5'-thioadenosine (mta) to adenine and 5-methylthioribose-1-phosphate. involved in the breakdown of mta, a major by-product of polyamine biosynthesis. responsible for the first step in the methionine salvage pathway after mta has been generated from s-adenosylmethionine. has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.;Species reactivity: Mouse;Application: ELISA;Assay info: ;Sensitivity: < 0.053ng/mL

Description: Description of target: Catalyzes the reversible phosphorylation of s-methyl-5'-thioadenosine (mta) to adenine and 5-methylthioribose-1-phosphate. involved in the breakdown of mta, a major by-product of polyamine biosynthesis. responsible for the first step in the methionine salvage pathway after mta has been generated from s-adenosylmethionine. has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.;Species reactivity: Mouse;Application: ;Assay info: Quantitative Sandwich ELISA;Sensitivity: <0.053ng/mL

Description: A polyclonal antibody against MTAP. Recognizes MTAP from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IF; Recommended dilution: WB:1:2000-1:10000, IF:1:50-1:200

Description: Affinity purified Rabbit polyclonal MTAP antibody

Description: Recognizes a protein of 31kDa, which is identified as MTAP (5'-deoxy-5'-methylthioadenosine phosphorylase). It catalyzes the reversible phosphorolysis of methylthioadenosine, which is important in polyamine metabolism and for the salvage of adenine and methionine. The gene encoding MTAP is linked to the tumor suppressor gene, p16INK4A. Deficient levels of MTAP can occur in cancers primarily through co-deletion of the MTAP gene and the p16INK4A gene. Cells expressing MTAP and possessing adenine salvage pathway activity may be less susceptible to malignancy due to growth-inhibitory actions of agents (e.g. antifolates), whose mechanism of action, in part, involves this de novo purine pathway.

Description: Recognizes a protein of 31kDa, which is identified as MTAP (5'-deoxy-5'-methylthioadenosine phosphorylase). It catalyzes the reversible phosphorolysis of methylthioadenosine, which is important in polyamine metabolism and for the salvage of adenine and methionine. The gene encoding MTAP is linked to the tumor suppressor gene, p16INK4A. Deficient levels of MTAP can occur in cancers primarily through co-deletion of the MTAP gene and the p16INK4A gene. Cells expressing MTAP and possessing adenine salvage pathway activity may be less susceptible to malignancy due to growth-inhibitory actions of agents (e.g. antifolates), whose mechanism of action, in part, involves this de novo purine pathway.